Popular on TelAve
- Experience Trembling Firsthand with the New AgeMan® Tremor Simulator
- The ITeam Ranked on Channel Partners 2025 MSP 501—Tech Industry's Most Prestigious List of Managed Service Providers Worldwide
- IRF Builders Forum Brings Global Leaders to Washington, D.C. to Advance Religious Freedom Through Cooperative Engagement
- Keepy Uppy™ by Ollyball Wins Prestigious 2025 Influencer Award from Clamour & The Toy Association; Announces Fall 2025 Launch at Target Stores
- Wealthywet's Miami Swim Week 2025 Debut Signals a New Era of Luxury in Swimwear
- TCAA Welcomes Adolfo Gomez Sanchez to Its Family of Talented Speakers
- Colorado Scenthound Locations Partner with Humane Colorado to Give Adopted Dogs a "Clean Start"
- databahn Launches GenAI Sales Intelligence Platform to Revolutionize Fortune 500 and Global 2000 Account Research
- BREAKING CONSUMER ALERT: Carvana's "Certified" Luxury SUV Buyer Exposes Legal & Mechanical Trauma 'Presses' Charges of Duress, Deception, and Delay
- Cyta Cyprus Selects Axiros' AXESS Platform for Cloud-Native, Data-Driven Device Management
Similar on TelAve
- SacraPod Suites Unveils AI-Powered 'Work + Rest' Smart Hospitality Model for Retrofitting Underused Motels Across the U.S
- New Release: 'The Invisible Alternative' Unveiled by Atrisk Corporation, Resilient
- Real Estate Experts Highlight Jersey Shore as a Smart Buy in 2025
- $18 Price Target Issued in New Research Report After $34 Million Revenue Forecast from Acquisition; $101.5 Million Net Revenue in 2025; NAS DAQ: IQST
- The AML Shop Launches New Financial Investigations Unit, Appoints Director to Lead the Initiative
- New Podcast "Spreading the Good BUZZ" Hosted by Josh and Heidi Case Launches July 7th with Explosive Global Reach and a Mission to Transform Lives
- Drone Light Shows Emerge as the New Standard in Live Event Entertainment
- Skyline Partners with ZenSpace to Offer Private Meeting Pods for Trade Show Exhibitors
- AI Innovation Dual-Strategy Business Model Focused on Real Estate Development for Strategic Expansion: OFA Group, (N A S D A Q: OFAL)
- Valley Sleep Therapy Expands to Prescott with New Location at Crossings Road
Breaking research could help to advance care for overdose patients who've taken xylazine
TelAve News/10847151
WASHINGTON, Nov. 20, 2024 ~ A recent study published in the journal Clinical Chemistry by researchers at the Washington University School of Medicine in St. Louis has shed light on the body's ability to clear xylazine, a popular emerging drug of abuse in the United States. The study, conducted by a team led by Bridgit Crews, PhD, found that it takes much longer for the human body to process xylazine than previously thought.
Xylazine is traditionally used as a tranquilizer in veterinary practice, but its use as a recreational drug has been on the rise. According to a report from the Centers for Disease Control and Prevention, between 2019 and 2022, there has been a 276% increase in detection of xylazine in fentanyl-associated overdose deaths. This is concerning because unlike opioids, Narcan does not work to revive individuals who have taken xylazine. Furthermore, there is limited research on how xylazine affects humans, making it difficult for healthcare providers to effectively treat patients who have used it.
In an effort to address this gap in knowledge about xylazine, Dr. Crews and her team set out to determine how long the drug remains in the body. They initially identified 493 patients who had used xylazine and also tested positive for fentanyl. After narrowing down their sample size based on specific criteria, they were left with 28 patients whose blood samples could be used to assess xylazine's half-life.
More on TelAve News
The half-life of a drug refers to the amount of time it takes for its concentration in the blood to decrease by half. By analyzing these blood samples over time, the researchers found that on average, xylazine has a half-life of 12 hours in humans. This is longer than what has been observed in animal studies and a previous case study involving one human subject which showed a half-life of nearly 5 hours.
This finding suggests that xylazine can remain in the human body for up to 2 days after an individual's last exposure, depending on the amount ingested. Additionally, the team identified metabolites of xylazine that could aid in its detection and improve clinical testing for the drug.
Dr. Crews emphasized the importance of this study in understanding the effects of xylazine on humans, especially in those who may chronically use fentanyl mixed with xylazine. She believes that a better understanding of typical xylazine concentrations and its duration in the body can help improve interpretation of clinical studies, establish appropriate cutoffs for surveillance, and inform treatment and monitoring strategies for patients at risk.
This novel study provides valuable insights into how the human body processes xylazine and highlights the need for further research on this emerging drug of abuse. The full study can be accessed at https://doi.org/10.1093/clinchem/hvae163.
Xylazine is traditionally used as a tranquilizer in veterinary practice, but its use as a recreational drug has been on the rise. According to a report from the Centers for Disease Control and Prevention, between 2019 and 2022, there has been a 276% increase in detection of xylazine in fentanyl-associated overdose deaths. This is concerning because unlike opioids, Narcan does not work to revive individuals who have taken xylazine. Furthermore, there is limited research on how xylazine affects humans, making it difficult for healthcare providers to effectively treat patients who have used it.
In an effort to address this gap in knowledge about xylazine, Dr. Crews and her team set out to determine how long the drug remains in the body. They initially identified 493 patients who had used xylazine and also tested positive for fentanyl. After narrowing down their sample size based on specific criteria, they were left with 28 patients whose blood samples could be used to assess xylazine's half-life.
More on TelAve News
- $18 Price Target Issued in New Research Report After $34 Million Revenue Forecast from Acquisition; $101.5 Million Net Revenue in 2025; NAS DAQ: IQST
- West Dentistry Welcomes New Oral Surgeon to Enhance Patient Care
- The AML Shop Launches New Financial Investigations Unit, Appoints Director to Lead the Initiative
- Raidium révolutionne le diagnostic de la Sclérose en Plaques en partenariat avec l'Hôpital Fondation Adolphe de Rothschild
- New Podcast "Spreading the Good BUZZ" Hosted by Josh and Heidi Case Launches July 7th with Explosive Global Reach and a Mission to Transform Lives
The half-life of a drug refers to the amount of time it takes for its concentration in the blood to decrease by half. By analyzing these blood samples over time, the researchers found that on average, xylazine has a half-life of 12 hours in humans. This is longer than what has been observed in animal studies and a previous case study involving one human subject which showed a half-life of nearly 5 hours.
This finding suggests that xylazine can remain in the human body for up to 2 days after an individual's last exposure, depending on the amount ingested. Additionally, the team identified metabolites of xylazine that could aid in its detection and improve clinical testing for the drug.
Dr. Crews emphasized the importance of this study in understanding the effects of xylazine on humans, especially in those who may chronically use fentanyl mixed with xylazine. She believes that a better understanding of typical xylazine concentrations and its duration in the body can help improve interpretation of clinical studies, establish appropriate cutoffs for surveillance, and inform treatment and monitoring strategies for patients at risk.
This novel study provides valuable insights into how the human body processes xylazine and highlights the need for further research on this emerging drug of abuse. The full study can be accessed at https://doi.org/10.1093/clinchem/hvae163.
Filed Under: Business
0 Comments
Latest on TelAve News
- Chappaqua's Annual Townwide Summer Sale – Unbeatable Savings at Your Favorite Local Boutiques!
- Skyline Partners with ZenSpace to Offer Private Meeting Pods for Trade Show Exhibitors
- AI Innovation Dual-Strategy Business Model Focused on Real Estate Development for Strategic Expansion: OFA Group, (N A S D A Q: OFAL)
- Construcción del Corredor Norte–Sur (NSC) de Singapur
- New Report: Slip and Fall Accidents Rank as the Leading Cause of Construction Site Fatalities
- Get Your Cowboy Boots On! Causeway Country BBQ Music Festival Kicks Off September 12–14 in Ft. Pierce
- Retired Hobbyist Launches Bold Weekly Album Project Using AI Songwriting Tools
- DimHum Launches Revolutionary CrowdShipping Service
- Eolian Signs New Information Exchange Agreement with the U.S. Department of Defense for Technology Innovation
- Infinite Health Introduces Cutting-Edge Regenerative Medicine for Wound Care with Trip Goolsby, MD
- Top Dentist Concord CA, Smile Makers Dental Care, Celebrates 500 5-Star Reviews
- Bio-Inspired Technology-Dynamic and Adaptable for unknown real-world environments
- Michael Reafsnyder opens solo exhibition at Scott Richards Contemporary Art in San Francisco
- Valley Sleep Therapy Expands to Prescott with New Location at Crossings Road
- $17.4 Million Total Revenue for First Half of 2025 (up 31.8% YOY) for Global Wet Trades Services Provider with High Value Bitcoin Investments
- $12.8 Million Net Revenue for 2024 for Cloud-Based Crowdsourcing Recruitment and SaaS-Enabled HR Solutions Provider: Baiya International Group Inc
- Hire Virtue Announces Executive Sponsorship Opportunity for Houston Hiring Blitz & Job Fair on August 6, 2025
- Inked & Maxim Model Teisha Mechetti Turns Heads—And Builds Community Impact
- Plan to Launch Silo Technologies' Cybersecurity Pilot Program for Ultimate Nationwide Deployment via Exclusive Partnership: Stock Symbol: BULT
- Robert Michael & Co. Real Estate Team Celebrates Industry Recognition and Showcases Premier Central Florida Listings